Ethanolic Root Extract of Urtica dioica Exhibits Pro-fertility and Antioxidant Activities in Female Albino Rats

Aims: To determine the effect of ethanolic extract Urtica dioica roots on reproductive hormones and antioxidant enzymes in female Wistar rats.
 Study Design: Experimental Research.
 Place Duration Study: Department Biochemistry, Lagos State University, Nigeria between November 2019 February 2020.
 Methodology: A total 40 rats used, were divided into eight groups 5 rats. The study was carried out for a period 21 days, induced with levonorgestrel 7 days after which administered 14 compared against vehicle, controls. Hormonal level estimation (Progesterone, estradiol, prolactin testosterone) in-vivo enzyme activity (catalase alkaline phosphatase activity) estimated using standard procedures.
 Results: administration showed no statistically significant difference estradiol levels across all groups. Progesterone decreased significantly (p<0.05) to controls while testosterone also decreased, although not significant. increased catalase activities IHD group control.
 Conclusion: exhibits pro-fertility activities.